Mepazine
A phenothiazine antipsychotic used to treat schizophrenia and other psychotic disorders. It works by blocking dopamine receptors in the brain to reduce symptoms such as hallucinations and delusions.
आणविक भार
310.5000 g/mol
LogP
5.60
TPSA
31.80 Ų
लिपिंस्की RO5
उत्तीर्ण
क्रिया का तंत्र
Blocks dopamine D2 receptors in the mesolimbic pathway, reducing excessive dopaminergic neurotransmission associated with psychotic symptoms. Many also antagonize serotonin 5-HT2A receptors, which may improve negative symptoms and reduce extrapyramidal side effects.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Blocks dopamine D2 receptors in the mesolimbic pathway, reducing excessive dopaminergic neurotransmission associated with psychotic symptoms. Many also antagonize serotonin 5-HT2A receptors, which may improve negative symptoms and reduce extrapyramidal …
2D संरचना
Cite this structure
Embed this structure
SMILES
CN1CCCC(CN2c3ccccc3Sc3ccccc32)C1
InChI
InChI=1S/C19H22N2S/c1-20-12-6-7-15(13-20)14-21-16-8-2-4-10-18(16)22-19-11-5-3-9-17(19)21/h2-5,8-11,15H,6-7,12-14H2,1H3
Molecular Formula
C19H22N2S
HBD / HBA
- / 3
घूर्णनीय बंधन
2
भारी परमाणु
22
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
अक्सर पूछे जाने वाले प्रश्न
A phenothiazine antipsychotic used to treat schizophrenia and other psychotic disorders. It works by blocking dopamine receptors in the brain to reduce symptoms such as hallucinations and delusions.
Blocks dopamine D2 receptors in the mesolimbic pathway, reducing excessive dopaminergic neurotransmission associated with psychotic symptoms. Many also antagonize serotonin 5-HT2A receptors, which may improve negative symptoms and reduce extrapyramidal side effects.
Yes, Mepazine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL395110. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 6075. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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