Nefazodone

CHEMBL623 Phase 4 अनुमोदित Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

470.0 g/mol

LogP

4.3

Phase

4

This antidepressant is used to treat major depression by affecting the balance of serotonin and norepinephrine in the brain. Due to rare but serious liver toxicity risks, its use has declined significantly and requires careful medical monitoring.

आणविक भार

470.0000 g/mol

LogP

4.30

TPSA

51.60 Å²

लिपिंस्की RO5

उत्तीर्ण

चिकित्सीय क्षेत्र

जनरलाइज़्ड एंग्ज़ाइटी डिसऑर्डर मेजर डिप्रेसिव डिसऑर्डर

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D संरचना

SVG PNG

Cite this structure

Embed this structure

SMILES

CCc1nn(CCCN2CCN(c3cccc(Cl)c3)CC2)c(=O)n1CCOc1ccccc1

InChI

InChI=1S/C25H32ClN5O2/c1-2-24-27-31(25(32)30(24)18-19-33-23-10-4-3-5-11-23)13-7-12-28-14-16-29(17-15-28)22-9-6-8-21(26)20-22/h3-6,8-11,20H,2,7,12-19H2,1H3

Molecular Formula

C25H32ClN5O2

HBD / HBA

- / 5

घूर्णनीय बंधन

10

भारी परमाणु

33

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

अक्सर पूछे जाने वाले प्रश्न

This antidepressant is used to treat major depression by affecting the balance of serotonin and norepinephrine in the brain. Due to rare but serious liver toxicity risks, its use has declined significantly and requires careful medical monitoring.

Yes, Nefazodone is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL623. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 4449. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

PillFYI

रोगी-अनुकूल जानकारी खोज रहे हैं?

Nefazodone PillFYI पर

संरचना

त्वरित डेटा

सूत्र: C25H32ClN5O2

बाहरी लिंक

Cite

BibTeX, APA, MLA, Chicago, IEEE, Harvard

चिकित्सा अस्वीकरण

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.