Nintedanib

CHEMBL502835 Phase 4 अनुमोदित Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

539.6 g/mol

LogP

4.3

Phase

4

A targeted therapy that blocks multiple growth factor receptors involved in the development of new blood vessels that tumors need to grow.

आणविक भार

539.6000 g/mol

LogP

4.30

TPSA

101.00 Å²

लिपिंस्की RO5

उत्तीर्ण

चिकित्सीय क्षेत्र

अल्ज़ाइमर रोग इंफ्लेमेटरी बाउल डिज़ीज़ ओवेरियन कैंसर कोलोरेक्टल कैंसर क्रॉनिक ऑब्सट्रक्टिव पल्मोनरी डिज़ीज़ (COPD) क्रॉनिक किडनी डिज़ीज़ गैस्ट्रोइसोफेजियल रिफ्लक्स रोग थायरॉइड कैंसर नॉन-अल्कोहलिक फैटी लिवर डिज़ीज़ नॉन-स्मॉल सेल लंग कैंसर पार्किंसन रोग मेलानोमा लिम्फोमा ल्यूकेमिया श्वसन रोग संक्रामक रोग स्तन कैंसर हृदय-संवहनी रोग

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D संरचना

SVG PNG

Cite this structure

Embed this structure

SMILES

COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1

InChI

InChI=1S/C31H33N5O4/c1-34-15-17-36(18-16-34)20-27(37)35(2)24-12-10-23(11-13-24)32-29(21-7-5-4-6-8-21)28-25-14-9-22(31(39)40-3)19-26(25)33-30(28)38/h4-14,19,32H,15-18,20H2,1-3H3,(H,33,38)/b29-28-

Molecular Formula

C31H33N5O4

HBD / HBA

2 / 7

घूर्णनीय बंधन

8

भारी परमाणु

40

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

अक्सर पूछे जाने वाले प्रश्न

A targeted therapy that blocks multiple growth factor receptors involved in the development of new blood vessels that tumors need to grow.

Yes, Nintedanib is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL502835. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 135423438. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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संरचना

त्वरित डेटा

सूत्र: C31H33N5O4
पर्यायवाची: 1

बाहरी लिंक

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चिकित्सा अस्वीकरण

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.