Perphenazine

CHEMBL567 Phase 4 अनुमोदित Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

404.0 g/mol

LogP

4.2

Phase

4

Perphenazine is a typical antipsychotic belonging to the phenothiazine class that exerts its effects primarily by blocking dopamine D2 receptors in the mesolimbic and mesocortical pathways. It is used in the treatment of schizophrenia, bipolar disorder, and severe anxiety, and also possesses antiemetic properties due to its action on dopamine receptors in the chemoreceptor trigger zone.

आणविक भार

404.0000 g/mol

LogP

4.20

TPSA

55.30 Å²

लिपिंस्की RO5

उत्तीर्ण

चिकित्सीय क्षेत्र

जनरलाइज़्ड एंग्ज़ाइटी डिसऑर्डर बाइपोलर डिसऑर्डर मोटापा सिज़ोफ्रेनिया स्ट्रोक

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D संरचना

SVG PNG

Cite this structure

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SMILES

OCCN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc32)CC1

InChI

InChI=1S/C21H26ClN3OS/c22-17-6-7-21-19(16-17)25(18-4-1-2-5-20(18)27-21)9-3-8-23-10-12-24(13-11-23)14-15-26/h1-2,4-7,16,26H,3,8-15H2

Molecular Formula

C21H26ClN3OS

HBD / HBA

1 / 5

घूर्णनीय बंधन

6

भारी परमाणु

27

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

अक्सर पूछे जाने वाले प्रश्न

Perphenazine is a typical antipsychotic belonging to the phenothiazine class that exerts its effects primarily by blocking dopamine D2 receptors in the mesolimbic and mesocortical pathways. It is used in the treatment of schizophrenia, bipolar disorder, and severe anxiety, and also possesses antiemetic properties due to its action on dopamine receptors in the chemoreceptor trigger zone.

Yes, Perphenazine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL567. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 4748. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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संरचना

त्वरित डेटा

सूत्र: C21H26ClN3OS

बाहरी लिंक

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चिकित्सा अस्वीकरण

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.