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Pranlukast

CHEMBL21333 Phase 4 अनुमोदित Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
481.5 g/mol
LogP
4.2
Phase
4

Pranlukast is a cysteinyl leukotriene receptor-1 (CysLT1) antagonist that blocks the bronchoconstrictor and pro-inflammatory actions of leukotrienes C4, D4, and E4 in the airways, reducing asthma symptoms including bronchospasm, mucus secretion, and airway eosinophilia. It is used in Japan and other Asian countries for the maintenance treatment of asthma and allergic rhinitis.

आणविक भार

481.5000 g/mol

LogP

4.20

TPSA

119.00 Ų

लिपिंस्की RO5

उत्तीर्ण

चिकित्सीय क्षेत्र

अस्थमा

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D संरचना

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
O=C(Nc1cccc2c(=O)cc(-c3nnn[nH]3)oc12)c1ccc(OCCCCc2ccccc2)cc1

                

                

                
                

                    
InChI

                    
InChI=1S/C27H23N5O4/c33-23-17-24(26-29-31-32-30-26)36-25-21(23)10-6-11-22(25)28-27(34)19-12-14-20(15-13-19)35-16-5-4-9-18-7-2-1-3-8-18/h1-3,6-8,10-15,17H,4-5,9,16H2,(H,28,34)(H,29,30,31,32)

                

                

                

                    
                    

                        
Molecular Formula

                        
C27H23N5O4

                    

                    
                    

                        
HBD / HBA

                        
2 / 7

                    

                    
                    

                        
घूर्णनीय बंधन

                        
9

                    

                    
                    
                    

                        
भारी परमाणु

                        
36

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
अक्सर पूछे जाने वाले प्रश्न

                

                    
                    

                        
                        

                            
Pranlukast is a cysteinyl leukotriene receptor-1 (CysLT1) antagonist that blocks the bronchoconstrictor and pro-inflammatory actions of leukotrienes C4, D4, and E4 in the airways, reducing asthma symptoms including bronchospasm, mucus secretion, and airway eosinophilia. It is used in Japan and other Asian countries for the maintenance treatment of asthma and allergic rhinitis.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Pranlukast is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL21333.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 4887.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
चिकित्सा अस्वीकरण

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.