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Raltegravir

CHEMBL254316 Phase 4 अनुमोदित Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
444.4 g/mol
LogP
1.1
Phase
4

An antiretroviral medication belonging to the integrase inhibitor class, used as part of combination therapy to treat HIV infection by preventing the virus from inserting its genetic material into human cells. It is effective against HIV strains resistant to other drug classes.

आणविक भार

444.4000 g/mol

LogP

1.10

TPSA

150.00 Ų

लिपिंस्की RO5

उत्तीर्ण

चिकित्सीय क्षेत्र

HIV/एड्स ऑस्टियोपोरोसिस क्षय रोग (ट्यूबरकुलोसिस) जनरलाइज़्ड एंग्ज़ाइटी डिसऑर्डर नॉन-अल्कोहलिक फैटी लिवर डिज़ीज़ मल्टीपल स्क्लेरोसिस लिम्फोमा ल्यूकेमिया हाइपरलिपिडेमिया हृदय-संवहनी रोग हेपेटाइटिस C

क्रिया का तंत्र

Inhibits viral integrase, preventing the insertion of viral DNA into the host cell genome and blocking viral replication.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

तंत्र

Inhibits viral integrase, preventing the insertion of viral DNA into the host cell genome and blocking viral replication.

2D संरचना

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
Cc1nnc(C(=O)NC(C)(C)c2nc(C(=O)NCc3ccc(F)cc3)c(O)c(=O)n2C)o1

                

                

                
                

                    
InChI

                    
InChI=1S/C20H21FN6O5/c1-10-25-26-17(32-10)16(30)24-20(2,3)19-23-13(14(28)18(31)27(19)4)15(29)22-9-11-5-7-12(21)8-6-11/h5-8,28H,9H2,1-4H3,(H,22,29)(H,24,30)

                

                

                

                    
                    

                        
Molecular Formula

                        
C20H21FN6O5

                    

                    
                    

                        
HBD / HBA

                        
3 / 9

                    

                    
                    

                        
घूर्णनीय बंधन

                        
6

                    

                    
                    
                    

                        
भारी परमाणु

                        
32

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
अक्सर पूछे जाने वाले प्रश्न

                

                    
                    

                        
                        

                            
An antiretroviral medication belonging to the integrase inhibitor class, used as part of combination therapy to treat HIV infection by preventing the virus from inserting its genetic material into human cells. It is effective against HIV strains resistant to other drug classes.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Inhibits viral integrase, preventing the insertion of viral DNA into the host cell genome and blocking viral replication.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Raltegravir is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
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                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL254316.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 54671008.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
चिकित्सा अस्वीकरण

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.