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Sodium Phenylacetate

CHEMBL1200358 Phase 4 अनुमोदित Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
158.1 g/mol
LogP
—
Phase
4

Sodium phenylacetate is a nitrogen-scavenging agent used in combination with sodium benzoate for the emergency treatment of acute hyperammonemia in patients with urea cycle disorders. Phenylacetate conjugates with glutamine (via phenylacetylglutamine) in the liver and kidney, enabling renal excretion of excess nitrogen that cannot be eliminated via the defective urea cycle. The combination product (Ammonul) is administered intravenously for acute hyperammonemic crisis.

आणविक भार

158.1300 g/mol

TPSA

40.10 Ų

चिकित्सीय क्षेत्र

Bladder Cancer Pain Management Rheumatoid Arthritis Migraine Generalized Anxiety Disorder Breast Cancer Gout Chronic Pain

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D संरचना

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
O=C([O-])Cc1ccccc1.[Na+]

                

                

                
                

                    
InChI

                    
InChI=1S/C8H8O2.Na/c9-8(10)6-7-4-2-1-3-5-7;/h1-5H,6H2,(H,9,10);/q;+1/p-1

                

                

                

                    
                    

                        
Molecular Formula

                        
C8H7NaO2

                    

                    
                    

                        
HBD / HBA

                        
- / 2

                    

                    
                    

                        
घूर्णनीय बंधन

                        
2

                    

                    
                    
                    

                        
भारी परमाणु

                        
11

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
अक्सर पूछे जाने वाले प्रश्न

                

                    
                    

                        
                        

                            
Sodium phenylacetate is a nitrogen-scavenging agent used in combination with sodium benzoate for the emergency treatment of acute hyperammonemia in patients with urea cycle disorders. Phenylacetate conjugates with glutamine (via phenylacetylglutamine) in the liver and kidney, enabling renal excretion of excess nitrogen that cannot be eliminated via the defective urea cycle. The combination product (Ammonul) is administered intravenously for acute hyperammonemic crisis.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Sodium Phenylacetate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1200358.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 23690424.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
चिकित्सा अस्वीकरण

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.