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Talquetamab

CHEMBL4594503 Phase 4 अनुमोदित Antibody
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
— g/mol
LogP
—
Phase
4

Talquetamab is a bispecific T-cell engager antibody that simultaneously binds to GPRC5D on multiple myeloma cells and CD3 on T cells, redirecting cytotoxic T cells to kill tumor cells. It is approved for relapsed or refractory multiple myeloma after multiple prior lines of therapy, and is under investigation for leukemia. Its target, GPRC5D, is highly expressed on myeloma cells and plasma cells, providing a selective therapeutic window.

चिकित्सीय क्षेत्र

ल्यूकेमिया

क्रिया का तंत्र

As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

तंत्र

As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.

HBD / HBA

- / -

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

अक्सर पूछे जाने वाले प्रश्न

Talquetamab is a bispecific T-cell engager antibody that simultaneously binds to GPRC5D on multiple myeloma cells and CD3 on T cells, redirecting cytotoxic T cells to kill tumor cells. It is approved for relapsed or refractory multiple myeloma after multiple prior lines of therapy, and is under investigation for leukemia. Its target, GPRC5D, is highly expressed on myeloma cells and plasma cells, providing a selective therapeutic window.

As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.

Yes, Talquetamab is an approved drug. It has reached clinical phase 4. It is classified as a Antibody.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL4594503. Open-access bioactivity database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.

चिकित्सा अस्वीकरण

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.