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Tasimelteon

CHEMBL2103822 Phase 4 अनुमोदित Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
245.3 g/mol
LogP
2.2
Phase
4

Tasimelteon is a selective melatonin receptor agonist (MT1 and MT2) approved for the treatment of non-24-hour sleep-wake disorder, a circadian rhythm disorder particularly prevalent in totally blind individuals without light perception. It synchronizes the circadian clock by mimicking the endogenous action of melatonin on suprachiasmatic nucleus receptors. It is also being studied for major depressive disorder and other circadian-related conditions.

आणविक भार

245.3200 g/mol

LogP

2.20

TPSA

38.30 Ų

लिपिंस्की RO5

उत्तीर्ण

चिकित्सीय क्षेत्र

अनिद्रा मेजर डिप्रेसिव डिसऑर्डर

क्रिया का तंत्र

Binds to and activates its target receptor, mimicking the action of the endogenous ligand to produce a specific physiological response.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

तंत्र

Binds to and activates its target receptor, mimicking the action of the endogenous ligand to produce a specific physiological response.

2D संरचना

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
CCC(=O)NC[C@@H]1C[C@H]1c1cccc2c1CCO2

                

                

                
                

                    
InChI

                    
InChI=1S/C15H19NO2/c1-2-15(17)16-9-10-8-13(10)11-4-3-5-14-12(11)6-7-18-14/h3-5,10,13H,2,6-9H2,1H3,(H,16,17)/t10-,13+/m0/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C15H19NO2

                    

                    
                    

                        
HBD / HBA

                        
1 / 2

                    

                    
                    

                        
घूर्णनीय बंधन

                        
4

                    

                    
                    
                    

                        
भारी परमाणु

                        
18

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
अक्सर पूछे जाने वाले प्रश्न

                

                    
                    

                        
                        

                            
Tasimelteon is a selective melatonin receptor agonist (MT1 and MT2) approved for the treatment of non-24-hour sleep-wake disorder, a circadian rhythm disorder particularly prevalent in totally blind individuals without light perception. It synchronizes the circadian clock by mimicking the endogenous action of melatonin on suprachiasmatic nucleus receptors. It is also being studied for major depressive disorder and other circadian-related conditions.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Binds to and activates its target receptor, mimicking the action of the endogenous ligand to produce a specific physiological response.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Tasimelteon is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL2103822.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 10220503.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
चिकित्सा अस्वीकरण

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.