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Thalidomide

CHEMBL468 Phase 4 अनुमोदित Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
258.2 g/mol
LogP
0.3
Phase
4

This medication has a complex history — once withdrawn due to causing severe birth defects, it is now used under strict controls to treat multiple myeloma and a complication of leprosy called erythema nodosum leprosum. It works partly by modulating the immune system and blocking new blood vessel growth that tumors need to grow. It is available only through a special restricted program, and must never be taken during pregnancy.

आणविक भार

258.2300 g/mol

LogP

0.30

TPSA

83.60 Ų

लिपिंस्की RO5

उत्तीर्ण

चिकित्सीय क्षेत्र

अग्नाशय कैंसर अल्ज़ाइमर रोग इंफ्लेमेटरी बाउल डिज़ीज़ उच्च रक्तचाप एंडोमेट्रियोसिस ओवेरियन कैंसर कोलोरेक्टल कैंसर क्रॉनिक किडनी डिज़ीज़ क्षय रोग (ट्यूबरकुलोसिस) थायरॉइड कैंसर दर्द प्रबंधन दीर्घकालिक दर्द नॉन-अल्कोहलिक फैटी लिवर डिज़ीज़ नॉन-स्मॉल सेल लंग कैंसर प्रोस्टेट कैंसर मिर्गी (एपिलेप्सी) मूत्राशय कैंसर मेलानोमा लिम्फोमा ल्यूकेमिया सिस्टेमिक ल्यूपस एरिथेमेटोसस सोरायसिस स्तन कैंसर हृदय विफलता हेपेटाइटिस C

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D संरचना

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
O=C1CCC(N2C(=O)c3ccccc3C2=O)C(=O)N1

                

                

                
                

                    
InChI

                    
InChI=1S/C13H10N2O4/c16-10-6-5-9(11(17)14-10)15-12(18)7-3-1-2-4-8(7)13(15)19/h1-4,9H,5-6H2,(H,14,16,17)

                

                

                

                    
                    

                        
Molecular Formula

                        
C13H10N2O4

                    

                    
                    

                        
HBD / HBA

                        
1 / 4

                    

                    
                    

                        
घूर्णनीय बंधन

                        
1

                    

                    
                    
                    

                        
भारी परमाणु

                        
19

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
अक्सर पूछे जाने वाले प्रश्न

                

                    
                    

                        
                        

                            
This medication has a complex history — once withdrawn due to causing severe birth defects, it is now used under strict controls to treat multiple myeloma and a complication of leprosy called erythema nodosum leprosum. It works partly by modulating the immune system and blocking new blood vessel growth that tumors need to grow. It is available only through a special restricted program, and must never be taken during pregnancy.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Thalidomide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
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                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL468.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 5426.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
चिकित्सा अस्वीकरण

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.