Thioguanine

CHEMBL727 Phase 4 अनुमोदित Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

167.2 g/mol

LogP

-0.1

Phase

4

This chemotherapy medication interferes with DNA synthesis in rapidly dividing cancer cells and is used to treat certain types of leukemia. It belongs to the thiopurine class and is converted inside cells into compounds that block DNA and RNA production. Regular blood count monitoring is essential as it can significantly suppress the bone marrow.

आणविक भार

167.1900 g/mol

LogP

-0.10

TPSA

111.00 Å²

लिपिंस्की RO5

उत्तीर्ण

चिकित्सीय क्षेत्र

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Non-Small Cell Lung Cancer Inflammatory Bowel Disease Lymphoma Breast Cancer Malaria Prostate Cancer Colorectal Cancer Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D संरचना

SVG PNG

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SMILES

Nc1nc2[nH]cnc2c(=S)[nH]1

InChI

InChI=1S/C5H5N5S/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)

Molecular Formula

C5H5N5S

HBD / HBA

3 / 2

घूर्णनीय बंधन

0

भारी परमाणु

11

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

अक्सर पूछे जाने वाले प्रश्न

This chemotherapy medication interferes with DNA synthesis in rapidly dividing cancer cells and is used to treat certain types of leukemia. It belongs to the thiopurine class and is converted inside cells into compounds that block DNA and RNA production. Regular blood count monitoring is essential as it can significantly suppress the bone marrow.

Yes, Thioguanine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL727. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 2723601. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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संरचना

त्वरित डेटा

सूत्र: C5H5N5S
पर्यायवाची: 1

बाहरी लिंक

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चिकित्सा अस्वीकरण

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.