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Tocofersolan

CHEMBL2108106 Phase 4 अनुमोदित Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
— g/mol
LogP
—
Phase
4

Tocofersolan (TPGS, d-alpha-tocopheryl polyethylene glycol 1000 succinate) is a water-soluble form of vitamin E (alpha-tocopherol) conjugated to polyethylene glycol via a succinate ester, used to treat vitamin E deficiency in children with congenital chronic cholestasis or hereditary chronic cholestasis where fat-soluble vitamin absorption is severely impaired. Its water-soluble nature allows intestinal absorption independent of bile acids, which are deficient in cholestatic liver disease. It is also used as a pharmaceutical solubilizer and bioavailability enhancer for poorly water-soluble drugs.

चिकित्सीय क्षेत्र

मलेरिया

क्रिया का तंत्र

Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

तंत्र

Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

HBD / HBA

- / -

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

अक्सर पूछे जाने वाले प्रश्न

Tocofersolan (TPGS, d-alpha-tocopheryl polyethylene glycol 1000 succinate) is a water-soluble form of vitamin E (alpha-tocopherol) conjugated to polyethylene glycol via a succinate ester, used to treat vitamin E deficiency in children with congenital chronic cholestasis or hereditary chronic cholestasis where fat-soluble vitamin absorption is severely impaired. Its water-soluble nature allows intestinal absorption independent of bile acids, which are deficient in cholestatic liver disease. It is also used as a pharmaceutical solubilizer and bioavailability enhancer for poorly water-soluble drugs.

Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

Yes, Tocofersolan is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2108106. Open-access bioactivity database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.

चिकित्सा अस्वीकरण

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.