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Toremifene

CHEMBL1655 Phase 4 अनुमोदित Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
406.0 g/mol
LogP
7.2
Phase
4

This selective estrogen receptor modulator (SERM) is used to treat metastatic breast cancer in postmenopausal women whose tumors are estrogen receptor-positive. Like tamoxifen, it works by competing with estrogen to bind to its receptors in breast cancer cells, slowing their growth. It may slightly increase the risk of uterine cancer and blood clots with long-term use.

आणविक भार

406.0000 g/mol

LogP

7.20

TPSA

12.50 Ų

लिपिंस्की RO5

उत्तीर्ण

चिकित्सीय क्षेत्र

अग्नाशय कैंसर ऑस्टियोपोरोसिस ओवेरियन कैंसर कोलोरेक्टल कैंसर थायरॉइड कैंसर नॉन-स्मॉल सेल लंग कैंसर प्रोस्टेट कैंसर मूत्राशय कैंसर स्तन कैंसर

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D संरचना

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
CN(C)CCOc1ccc(/C(=C(/CCCl)c2ccccc2)c2ccccc2)cc1

                

                

                
                

                    
InChI

                    
InChI=1S/C26H28ClNO/c1-28(2)19-20-29-24-15-13-23(14-16-24)26(22-11-7-4-8-12-22)25(17-18-27)21-9-5-3-6-10-21/h3-16H,17-20H2,1-2H3/b26-25-

                

                

                

                    
                    

                        
Molecular Formula

                        
C26H28ClNO

                    

                    
                    

                        
HBD / HBA

                        
- / 2

                    

                    
                    

                        
घूर्णनीय बंधन

                        
9

                    

                    
                    
                    

                        
भारी परमाणु

                        
29

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
अक्सर पूछे जाने वाले प्रश्न

                

                    
                    

                        
                        

                            
This selective estrogen receptor modulator (SERM) is used to treat metastatic breast cancer in postmenopausal women whose tumors are estrogen receptor-positive. Like tamoxifen, it works by competing with estrogen to bind to its receptors in breast cancer cells, slowing their growth. It may slightly increase the risk of uterine cancer and blood clots with long-term use.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Toremifene is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1655.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 3005573.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
चिकित्सा अस्वीकरण

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.