💊 दवाएँ A-Z 🧬 लक्ष्य 🛠 उपकरण 📚 मार्गदर्शिकाएँ
सभी दवाएँ दवा वर्ग चिकित्सीय क्षेत्र दुष्प्रभाव
मार्गदर्शिकाएँ शब्दकोश समयरेखा
तुलनाएँ दवाओं की यात्राएँ दवा परिवार
🇺🇸 English 🇰🇷 한국어 🇯🇵 日本語 🇨🇳 中文简体 🇪🇸 Español 🇧🇷 Português 🇮🇳 हिन्दी 🇸🇦 العربية 🇫🇷 Français 🇷🇺 Русский 🇩🇪 Deutsch 🇹🇷 Türkçe 🇻🇳 Tiếng Việt 🇮🇩 Bahasa Indonesia 🇹🇭 ไทย

Triheptanoin

CHEMBL4297585 Phase 4 अनुमोदित Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
428.6 g/mol
LogP
7.3
Phase
4

Triheptanoin is a synthetic odd-chain medium-chain triglyceride (C7 fatty acid ester of glycerol) that is hydrolyzed to heptanoate, which undergoes anaplerotic metabolism to generate propionyl-CoA and acetyl-CoA, replenishing the Krebs cycle intermediates (anaplerosis) and providing an alternative energy substrate to glucose in metabolically compromised tissues. It is approved for long-chain fatty acid oxidation disorders (LC-FAOD) to reduce cardiomyopathy, myopathy, and hypoglycemic episodes, and is under investigation for pyruvate carboxylase deficiency, Huntington's disease, and heart failure. Its unique anaplerotic mechanism addresses fundamental energy metabolism defects in these conditions.

आणविक भार

428.6000 g/mol

LogP

7.30

TPSA

78.90 Ų

लिपिंस्की RO5

उत्तीर्ण

चिकित्सीय क्षेत्र

Epilepsy Migraine Heart Failure

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D संरचना

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
CCCCCCC(=O)OCC(COC(=O)CCCCCC)OC(=O)CCCCCC

                

                

                
                

                    
InChI

                    
InChI=1S/C24H44O6/c1-4-7-10-13-16-22(25)28-19-21(30-24(27)18-15-12-9-6-3)20-29-23(26)17-14-11-8-5-2/h21H,4-20H2,1-3H3

                

                

                

                    
                    

                        
Molecular Formula

                        
C24H44O6

                    

                    
                    

                        
HBD / HBA

                        
- / 6

                    

                    
                    

                        
घूर्णनीय बंधन

                        
23

                    

                    
                    
                    

                        
भारी परमाणु

                        
30

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
अक्सर पूछे जाने वाले प्रश्न

                

                    
                    

                        
                        

                            
Triheptanoin is a synthetic odd-chain medium-chain triglyceride (C7 fatty acid ester of glycerol) that is hydrolyzed to heptanoate, which undergoes anaplerotic metabolism to generate propionyl-CoA and acetyl-CoA, replenishing the Krebs cycle intermediates (anaplerosis) and providing an alternative energy substrate to glucose in metabolically compromised tissues. It is approved for long-chain fatty acid oxidation disorders (LC-FAOD) to reduce cardiomyopathy, myopathy, and hypoglycemic episodes, and is under investigation for pyruvate carboxylase deficiency, Huntington's disease, and heart failure. Its unique anaplerotic mechanism addresses …

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Triheptanoin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL4297585.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 69286.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
चिकित्सा अस्वीकरण

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.