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Valacyclovir

CHEMBL1349 Phase 4 अनुमोदित Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
324.3 g/mol
LogP
-0.9
Phase
4

This antiviral medication is a prodrug that is converted in the body into acyclovir, used to treat infections caused by herpes viruses including genital herpes, cold sores, shingles (herpes zoster), and chickenpox. It works by blocking the viral enzyme needed for the herpes virus to copy its DNA and reproduce. When taken daily as suppressive therapy, it can significantly reduce the frequency and severity of herpes outbreaks and lower the risk of transmitting the virus to others.

आणविक भार

324.3400 g/mol

LogP

-0.90

TPSA

147.00 Ų

लिपिंस्की RO5

उत्तीर्ण

चिकित्सीय क्षेत्र

HIV/एड्स अग्नाशय कैंसर ऑन्कोलॉजी ओवेरियन कैंसर कोलोरेक्टल कैंसर क्रॉनिक ऑब्सट्रक्टिव पल्मोनरी डिज़ीज़ (COPD) थायरॉइड कैंसर नॉन-स्मॉल सेल लंग कैंसर प्रोस्टेट कैंसर बाइपोलर डिसऑर्डर मूत्राशय कैंसर मेलानोमा ल्यूकेमिया सिज़ोफ्रेनिया स्तन कैंसर हेपेटाइटिस C

क्रिया का तंत्र

Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

तंत्र

Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.

2D संरचना

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
CC(C)[C@H](N)C(=O)OCCOCn1cnc2c(=O)nc(N)[nH]c21

                

                

                
                

                    
InChI

                    
InChI=1S/C13H20N6O4/c1-7(2)8(14)12(21)23-4-3-22-6-19-5-16-9-10(19)17-13(15)18-11(9)20/h5,7-8H,3-4,6,14H2,1-2H3,(H3,15,17,18,20)/t8-/m0/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C13H20N6O4

                    

                    
                    

                        
HBD / HBA

                        
3 / 7

                    

                    
                    

                        
घूर्णनीय बंधन

                        
8

                    

                    
                    
                    

                        
भारी परमाणु

                        
23

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
अक्सर पूछे जाने वाले प्रश्न

                

                    
                    

                        
                        

                            
This antiviral medication is a prodrug that is converted in the body into acyclovir, used to treat infections caused by herpes viruses including genital herpes, cold sores, shingles (herpes zoster), and chickenpox. It works by blocking the viral enzyme needed for the herpes virus to copy its DNA and reproduce. When taken daily as suppressive therapy, it can significantly reduce the frequency and severity of herpes outbreaks and lower the risk of transmitting the virus to others.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Valacyclovir is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1349.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 135398742.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
चिकित्सा अस्वीकरण

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.