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Verapamil

CHEMBL6966 Phase 4 अनुमोदित Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
454.6 g/mol
LogP
3.8
Phase
4

This calcium channel blocker is used to treat high blood pressure, certain heart rhythm disorders (including atrial fibrillation and supraventricular tachycardia), and angina (chest pain), and is also used to prevent migraine headaches and cluster headaches. It works by slowing the movement of calcium into heart and blood vessel muscle cells, causing the heart to beat more slowly and blood vessels to relax. It interacts with many medications, and grapefruit juice can increase its blood levels significantly.

आणविक भार

454.6000 g/mol

LogP

3.80

TPSA

64.00 Ų

लिपिंस्की RO5

उत्तीर्ण

चिकित्सीय क्षेत्र

अग्नाशय कैंसर अस्थमा उच्च रक्तचाप एट्रियल फ़िब्रिलेशन ओवेरियन कैंसर कोलोरेक्टल कैंसर क्रॉनिक ऑब्सट्रक्टिव पल्मोनरी डिज़ीज़ (COPD) क्रॉनिक किडनी डिज़ीज़ जनरलाइज़्ड एंग्ज़ाइटी डिसऑर्डर टाइप 2 मधुमेह थायरॉइड कैंसर दर्द प्रबंधन दीर्घकालिक दर्द नॉन-स्मॉल सेल लंग कैंसर प्रोस्टेट कैंसर माइग्रेन मिर्गी (एपिलेप्सी) मूत्राशय कैंसर मोटापा लिम्फोमा सिस्टेमिक ल्यूपस एरिथेमेटोसस स्ट्रोक स्तन कैंसर हृदय विफलता हृदय-संवहनी रोग

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D संरचना

SVG PNG

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SMILES

                    
COc1ccc(CCN(C)CCCC(C#N)(c2ccc(OC)c(OC)c2)C(C)C)cc1OC

                

                

                
                

                    
InChI

                    
InChI=1S/C27H38N2O4/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6/h9-12,17-18,20H,8,13-16H2,1-7H3

                

                

                

                    
                    

                        
Molecular Formula

                        
C27H38N2O4

                    

                    
                    

                        
HBD / HBA

                        
- / 6

                    

                    
                    

                        
घूर्णनीय बंधन

                        
13

                    

                    
                    
                    

                        
भारी परमाणु

                        
33

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
अक्सर पूछे जाने वाले प्रश्न

                

                    
                    

                        
                        

                            
This calcium channel blocker is used to treat high blood pressure, certain heart rhythm disorders (including atrial fibrillation and supraventricular tachycardia), and angina (chest pain), and is also used to prevent migraine headaches and cluster headaches. It works by slowing the movement of calcium into heart and blood vessel muscle cells, causing the heart to beat more slowly and blood vessels to relax. It interacts with many medications, and grapefruit juice can increase its blood levels significantly.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Verapamil is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
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                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL6966.
                Open-access bioactivity database.
            
        
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  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 2520.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
चिकित्सा अस्वीकरण

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.