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Vernakalant Hydrochloride

CHEMBL2107383 Phase 4 अनुमोदित Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
385.9 g/mol
LogP
—
Phase
4

Vernakalant hydrochloride is the hydrochloride salt of vernakalant, an atrial-selective antiarrhythmic agent approved for rapid cardioversion of recent-onset atrial fibrillation. It blocks atrial-specific potassium channels (IKur, IKAch) and sodium channels with use-dependent kinetics, terminating AF while sparing ventricular myocardium. The intravenous hydrochloride salt formulation enables rapid administration in clinical settings for acute AF management.

आणविक भार

385.9000 g/mol

TPSA

51.20 Ų

चिकित्सीय क्षेत्र

एट्रियल फ़िब्रिलेशन

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D संरचना

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
COc1ccc(CCO[C@@H]2CCCC[C@H]2N2CC[C@@H](O)C2)cc1OC.Cl

                

                

                
                

                    
InChI

                    
InChI=1S/C20H31NO4.ClH/c1-23-19-8-7-15(13-20(19)24-2)10-12-25-18-6-4-3-5-17(18)21-11-9-16(22)14-21;/h7-8,13,16-18,22H,3-6,9-12,14H2,1-2H3;1H/t16-,17-,18-;/m1./s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C20H32ClNO4

                    

                    
                    

                        
HBD / HBA

                        
2 / 5

                    

                    
                    

                        
घूर्णनीय बंधन

                        
7

                    

                    
                    
                    

                        
भारी परमाणु

                        
26

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
अक्सर पूछे जाने वाले प्रश्न

                

                    
                    

                        
                        

                            
Vernakalant hydrochloride is the hydrochloride salt of vernakalant, an atrial-selective antiarrhythmic agent approved for rapid cardioversion of recent-onset atrial fibrillation. It blocks atrial-specific potassium channels (IKur, IKAch) and sodium channels with use-dependent kinetics, terminating AF while sparing ventricular myocardium. The intravenous hydrochloride salt formulation enables rapid administration in clinical settings for acute AF management.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Vernakalant Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL2107383.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 9930048.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
चिकित्सा अस्वीकरण

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.