Acetaminophen vs Naproxen

## Acetaminophen vs Naproxen: Overview

This comparison examines the pharmacological differences between **Acetaminophen** and **Naproxen**.

## Mechanism of Action

**Acetaminophen**: Inhibits prostaglandin synthesis in the CNS and peripherally blocks pain impulse generation.

**Naproxen**: Non-selective COX inhibitor.

## Pharmacokinetics

**Half-life**: Acetaminophen — 1-4 hours; Naproxen — 12-17 hours.

## Chemical Properties

**Molecular Formula**: Acetaminophen — C8H9NO2; Naproxen — C14H14O3.

**Molecular Weight**: Acetaminophen — 151.1630 g/mol; Naproxen — 230.2590 g/mol.

**Type**: Acetaminophen — Small molecule; Naproxen — Small molecule.