Afatinib vs Losartan

## Afatinib vs Losartan: Overview

This comparison examines the pharmacological differences between **Afatinib** and **Losartan**.

## Mechanism of Action

**Afatinib**: Irreversible covalent inhibitor of ErbB family (EGFR/HER1, HER2, HER4) tyrosine kinases.

**Losartan**: Angiotensin II receptor type 1 antagonist.

## Pharmacokinetics

**Half-life**: Afatinib — 37 hours; Losartan — 2 hours.

## Chemical Properties

**Molecular Formula**: Afatinib — C24H25ClFN5O3; Losartan — C22H23ClN6O.

**Molecular Weight**: Afatinib — 485.9400 g/mol; Losartan — 422.9200 g/mol.

**Type**: Afatinib — Small molecule; Losartan — Small molecule.