Citalopram vs Hydrochlorothiazide

## Citalopram vs Hydrochlorothiazide: Overview

This comparison examines the pharmacological differences between **Citalopram** and **Hydrochlorothiazide**.

## Mechanism of Action

**Citalopram**: Selective serotonin reuptake inhibitor (SSRI); racemic mixture with escitalopram as active S-enantiomer.

**Hydrochlorothiazide**: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

## Pharmacokinetics

**Half-life**: Citalopram — 35 hours; Hydrochlorothiazide — 6-15 hours.

## Chemical Properties

**Molecular Formula**: Citalopram — C20H21FN2O; Hydrochlorothiazide — C7H8ClN3O4S2.

**Molecular Weight**: Citalopram — 324.3920 g/mol; Hydrochlorothiazide — 297.7400 g/mol.

**Type**: Citalopram — Small molecule; Hydrochlorothiazide — Small molecule.