Cyclosporine vs Fluconazole

## Cyclosporine vs Fluconazole: Overview

This comparison examines the pharmacological differences between **Cyclosporine** and **Fluconazole**.

## Mechanism of Action

**Cyclosporine**: Calcineurin inhibitor suppressing T-cell activation.

**Fluconazole**: Inhibits fungal CYP51 (lanosterol 14-alpha-demethylase).

## Pharmacokinetics

**Half-life**: Cyclosporine — 6-12 hours; Fluconazole — 30 hours.

## Chemical Properties

**Molecular Formula**: Cyclosporine — C62H111N11O12; Fluconazole — C13H12F2N6O.

**Molecular Weight**: Cyclosporine — 1202.6100 g/mol; Fluconazole — 306.2710 g/mol.

**Type**: Cyclosporine — Protein; Fluconazole — Small molecule.