Donepezil vs Duloxetine

## Donepezil vs Duloxetine: Overview

This comparison examines the pharmacological differences between **Donepezil** and **Duloxetine**.

## Mechanism of Action

**Donepezil**: Reversible acetylcholinesterase inhibitor.

**Duloxetine**: Serotonin-norepinephrine reuptake inhibitor (SNRI).

## Pharmacokinetics

**Half-life**: Donepezil — 70 hours; Duloxetine — 12 hours.

## Chemical Properties

**Molecular Formula**: Donepezil — C24H29NO3; Duloxetine — C18H19NOS.

**Molecular Weight**: Donepezil — 379.4920 g/mol; Duloxetine — 297.4150 g/mol.

**Type**: Donepezil — Small molecule; Duloxetine — Small molecule.