Hydrochlorothiazide vs Norfloxacin

## Hydrochlorothiazide vs Norfloxacin: Overview

This comparison examines the pharmacological differences between **Hydrochlorothiazide** and **Norfloxacin**.

## Mechanism of Action

**Hydrochlorothiazide**: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

**Norfloxacin**: Second-generation fluoroquinolone inhibiting bacterial DNA gyrase and topoisomerase IV.

## Pharmacokinetics

**Half-life**: Hydrochlorothiazide — 6-15 hours; Norfloxacin — 3-4 hours.

## Chemical Properties

**Molecular Formula**: Hydrochlorothiazide — C7H8ClN3O4S2; Norfloxacin — C16H18FN3O3.

**Molecular Weight**: Hydrochlorothiazide — 297.7400 g/mol; Norfloxacin — 319.3310 g/mol.

**Type**: Hydrochlorothiazide — Small molecule; Norfloxacin — Small molecule.