Irbesartan vs Losartan

## Irbesartan vs Losartan: Overview

This comparison examines the pharmacological differences between **Irbesartan** and **Losartan**.

## Mechanism of Action

**Irbesartan**: Selective non-competitive angiotensin II type 1 receptor antagonist.

**Losartan**: Angiotensin II receptor type 1 antagonist.

## Pharmacokinetics

**Half-life**: Irbesartan — 11-15 hours; Losartan — 2 hours.

## Chemical Properties

**Molecular Formula**: Irbesartan — C25H28N6O; Losartan — C22H23ClN6O.

**Molecular Weight**: Irbesartan — 428.5320 g/mol; Losartan — 422.9200 g/mol.

**Type**: Irbesartan — Small molecule; Losartan — Small molecule.