Metformin vs Trimethoprim

## Metformin vs Trimethoprim: Overview

This comparison examines the pharmacological differences between **Metformin** and **Trimethoprim**.

## Mechanism of Action

**Metformin**: Activates AMP-activated protein kinase, decreasing hepatic glucose production.

**Trimethoprim**: Dihydrofolate reductase inhibitor (bacterial selective).

## Pharmacokinetics

**Half-life**: Metformin — 4-9 hours; Trimethoprim — 8-10 hours.

## Chemical Properties

**Molecular Formula**: Metformin — C4H11N5; Trimethoprim — C14H18N4O3.

**Molecular Weight**: Metformin — 129.1640 g/mol; Trimethoprim — 290.3180 g/mol.

**Type**: Metformin — Small molecule; Trimethoprim — Small molecule.