Amineptine

CHEMBL418995 Phase 4 Disetujui Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

337.5 g/mol

LogP

2.1

Phase

4

A tricyclic antidepressant with a unique mechanism that selectively enhances dopamine reuptake inhibition, differing from most tricyclics which primarily target serotonin and norepinephrine systems. It was withdrawn from most markets due to its significant abuse potential and addiction liability.

Berat Molekul

337,5000 g/mol

LogP

2,10

TPSA

49,30 Å²

Lipinski RO5

Lulus

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Struktur 2D

SVG PNG

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SMILES

O=C(O)CCCCCCNC1c2ccccc2CCc2ccccc21

InChI

InChI=1S/C22H27NO2/c24-21(25)13-3-1-2-8-16-23-22-19-11-6-4-9-17(19)14-15-18-10-5-7-12-20(18)22/h4-7,9-12,22-23H,1-3,8,13-16H2,(H,24,25)

Molecular Formula

C22H27NO2

HBD / HBA

2 / 3

Ikatan yang Dapat Dirotasi

8

Atom Berat

25

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Pertanyaan yang Sering Diajukan

A tricyclic antidepressant with a unique mechanism that selectively enhances dopamine reuptake inhibition, differing from most tricyclics which primarily target serotonin and norepinephrine systems. It was withdrawn from most markets due to its significant abuse potential and addiction liability.

Yes, Amineptine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL418995. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 34870. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Struktur

Data Cepat

Rumus: C22H27NO2

Tautan Eksternal

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Penyangkalan Medis

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.