Atropine
A muscarinic receptor antagonist derived from the belladonna plant that blocks the effects of acetylcholine on the parasympathetic nervous system, increasing heart rate, drying secretions, and relaxing smooth muscle. It is used in emergencies for bradycardia and to reverse certain poisonings.
Berat Molekul
289,4000 g/mol
LogP
1,80
TPSA
49,80 Ų
Lipinski RO5
Lulus
Area Terapeutik
Mekanisme Kerja
Competitively blocks muscarinic acetylcholine receptors, reducing parasympathetic nervous system activity. Effects include decreased secretions, bronchodilation, and relaxation of smooth muscle.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Competitively blocks muscarinic acetylcholine receptors, reducing parasympathetic nervous system activity. Effects include decreased secretions, bronchodilation, and relaxation of smooth muscle.
Struktur 2D
Cite this structure
Embed this structure
SMILES
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2
InChI
InChI=1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15+,16?
Molecular Formula
C17H23NO3
HBD / HBA
1 / 4
Ikatan yang Dapat Dirotasi
5
Atom Berat
21
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Pertanyaan yang Sering Diajukan
A muscarinic receptor antagonist derived from the belladonna plant that blocks the effects of acetylcholine on the parasympathetic nervous system, increasing heart rate, drying secretions, and relaxing smooth muscle. It is used in emergencies for bradycardia and to reverse certain poisonings.
Competitively blocks muscarinic acetylcholine receptors, reducing parasympathetic nervous system activity. Effects include decreased secretions, bronchodilation, and relaxation of smooth muscle.
Yes, Atropine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL517712. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 174174. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
Embed This Widget
Add the script tag and a data attribute to embed this widget.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<div data-drugfyi="drug" data-slug="atropine"></div>Embed via iframe for maximum compatibility.
<iframe src="https://drugfyi.com/iframe/drug/atropine/" width="420" height="400" frameborder="0" style="border:0;border-radius:10px;max-width:100%" loading="lazy"></iframe>Paste this URL in WordPress, Medium, or any oEmbed-compatible platform.
https://drugfyi.com/drug/atropine/Add a dynamic SVG badge to your README or docs.
[](https://drugfyi.com/drug/atropine/)Use the native HTML custom element.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<drugfyi-drug slug="atropine"></drugfyi-drug>