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Benznidazole

CHEMBL110 Phase 4 Disetujui Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
260.2 g/mol
LogP
0.9
Phase
4

An antiparasitic agent that is the primary treatment for Chagas disease caused by Trypanosoma cruzi, working by generating reactive intermediates that damage the parasite's DNA and proteins. Early treatment during the acute phase offers the best chance of eliminating the infection.

Berat Molekul

260,2500 g/mol

LogP

0,90

TPSA

92,70 Ų

Lipinski RO5

Lulus

Mekanisme Kerja

Disrupts essential metabolic pathways or structural components of parasitic organisms, leading to paralysis, starvation, or death of the parasite.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mekanisme

Disrupts essential metabolic pathways or structural components of parasitic organisms, leading to paralysis, starvation, or death of the parasite.

Struktur 2D

SVG PNG

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SMILES

                    
O=C(Cn1ccnc1[N+](=O)[O-])NCc1ccccc1

                

                

                
                

                    
InChI

                    
InChI=1S/C12H12N4O3/c17-11(14-8-10-4-2-1-3-5-10)9-15-7-6-13-12(15)16(18)19/h1-7H,8-9H2,(H,14,17)

                

                

                

                    
                    

                        
Molecular Formula

                        
C12H12N4O3

                    

                    
                    

                        
HBD / HBA

                        
1 / 4

                    

                    
                    

                        
Ikatan yang Dapat Dirotasi

                        
4

                    

                    
                    
                    

                        
Atom Berat

                        
19

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Pertanyaan yang Sering Diajukan

                

                    
                    

                        
                        

                            
An antiparasitic agent that is the primary treatment for Chagas disease caused by Trypanosoma cruzi, working by generating reactive intermediates that damage the parasite's DNA and proteins. Early treatment during the acute phase offers the best chance of eliminating the infection.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Disrupts essential metabolic pathways or structural components of parasitic organisms, leading to paralysis, starvation, or death of the parasite.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Benznidazole is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL110.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 31593.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Penyangkalan Medis

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.