Betamethasone Dipropionate
A high-potency topical corticosteroid ester used to treat skin conditions including psoriasis, eczema, and contact dermatitis. It penetrates the skin well, providing strong anti-inflammatory and antipruritic effects. Use on the face, skin folds, or in children should be limited due to higher absorption risks.
Berat Molekul
504,6000 g/mol
LogP
3,60
TPSA
107,00 Ų
Lipinski RO5
Lulus
Area Terapeutik
Mekanisme Kerja
Binds to intracellular glucocorticoid receptors, translocating to the nucleus to modulate gene transcription. This suppresses multiple inflammatory genes encoding cytokines, chemokines, and adhesion molecules while inducing anti-inflammatory proteins.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Binds to intracellular glucocorticoid receptors, translocating to the nucleus to modulate gene transcription. This suppresses multiple inflammatory genes encoding cytokines, chemokines, and adhesion molecules while inducing anti-inflammatory proteins.
Struktur 2D
Cite this structure
Embed this structure
SMILES
CCC(=O)OCC(=O)[C@@]1(OC(=O)CC)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C
InChI
InChI=1S/C28H37FO7/c1-6-23(33)35-15-22(32)28(36-24(34)7-2)16(3)12-20-19-9-8-17-13-18(30)10-11-25(17,4)27(19,29)21(31)14-26(20,28)5/h10-11,13,16,19-21,31H,6-9,12,14-15H2,1-5H3/t16-,19-,20-,21-,25-,26-,27-,28-/m0/s1
Molecular Formula
C28H37FO7
HBD / HBA
1 / 8
Ikatan yang Dapat Dirotasi
8
Atom Berat
36
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Pertanyaan yang Sering Diajukan
A high-potency topical corticosteroid ester used to treat skin conditions including psoriasis, eczema, and contact dermatitis. It penetrates the skin well, providing strong anti-inflammatory and antipruritic effects. Use on the face, skin folds, or in children should be limited due to higher absorption risks.
Binds to intracellular glucocorticoid receptors, translocating to the nucleus to modulate gene transcription. This suppresses multiple inflammatory genes encoding cytokines, chemokines, and adhesion molecules while inducing anti-inflammatory proteins.
Yes, Betamethasone Dipropionate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200384. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 21800. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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