Betamethasone Phosphoric Acid
An acidic precursor form related to betamethasone sodium phosphate, a water-soluble corticosteroid used for injection or topical applications. It converts to active betamethasone in the body to reduce inflammation. This form allows for rapid onset of anti-inflammatory activity.
Berat Molekul
472,4000 g/mol
LogP
0,10
TPSA
141,00 Ų
Lipinski RO5
Lulus
Mekanisme Kerja
Binds to intracellular glucocorticoid receptors, translocating to the nucleus to modulate gene transcription. This suppresses multiple inflammatory genes encoding cytokines, chemokines, and adhesion molecules while inducing anti-inflammatory proteins.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Binds to intracellular glucocorticoid receptors, translocating to the nucleus to modulate gene transcription. This suppresses multiple inflammatory genes encoding cytokines, chemokines, and adhesion molecules while inducing anti-inflammatory proteins.
Struktur 2D
Cite this structure
Embed this structure
SMILES
C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)COP(=O)(O)O
InChI
InChI=1S/C22H30FO8P/c1-12-8-16-15-5-4-13-9-14(24)6-7-19(13,2)21(15,23)17(25)10-20(16,3)22(12,27)18(26)11-31-32(28,29)30/h6-7,9,12,15-17,25,27H,4-5,8,10-11H2,1-3H3,(H2,28,29,30)/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1
Molecular Formula
C22H30FO8P
HBD / HBA
4 / 9
Ikatan yang Dapat Dirotasi
4
Atom Berat
32
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Pertanyaan yang Sering Diajukan
An acidic precursor form related to betamethasone sodium phosphate, a water-soluble corticosteroid used for injection or topical applications. It converts to active betamethasone in the body to reduce inflammation. This form allows for rapid onset of anti-inflammatory activity.
Binds to intracellular glucocorticoid receptors, translocating to the nucleus to modulate gene transcription. This suppresses multiple inflammatory genes encoding cytokines, chemokines, and adhesion molecules while inducing anti-inflammatory proteins.
Yes, Betamethasone Phosphoric Acid is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201207. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 107782. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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