Bretylium Tosylate
The tosylate salt of bretylium, an antiarrhythmic agent used historically in emergency management of ventricular fibrillation and tachycardia. It stabilizes the heart's electrical activity by depleting norepinephrine from nerve terminals. It is no longer commercially available in most countries.
Berat Molekul
414,4000 g/mol
TPSA
65,60 Ų
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Struktur 2D
Cite this structure
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SMILES
CC[N+](C)(C)Cc1ccccc1Br.Cc1ccc(S(=O)(=O)[O-])cc1
InChI
InChI=1S/C11H17BrN.C7H8O3S/c1-4-13(2,3)9-10-7-5-6-8-11(10)12;1-6-2-4-7(5-3-6)11(8,9)10/h5-8H,4,9H2,1-3H3;2-5H,1H3,(H,8,9,10)/q+1;/p-1
Molecular Formula
C18H24BrNO3S
HBD / HBA
- / 3
Ikatan yang Dapat Dirotasi
3
Atom Berat
24
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Pertanyaan yang Sering Diajukan
The tosylate salt of bretylium, an antiarrhythmic agent used historically in emergency management of ventricular fibrillation and tachycardia. It stabilizes the heart's electrical activity by depleting norepinephrine from nerve terminals. It is no longer commercially available in most countries.
Yes, Bretylium Tosylate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1095292. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 6100. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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