Bretylium

CHEMBL1199080 Phase 4 Disetujui Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

243.2 g/mol

LogP

2.8

Phase

4

An older antiarrhythmic medication that was used to treat life-threatening ventricular arrhythmias, including ventricular fibrillation, primarily in emergency settings. It works by blocking the release of norepinephrine from sympathetic nerve endings. It has largely been replaced by more effective and better-studied agents in advanced cardiac life support.

Berat Molekul

243,1600 g/mol

LogP

2,80

TPSA

0,00 Å²

Lipinski RO5

Lulus

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Struktur 2D

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SMILES

CC[N+](C)(C)Cc1ccccc1Br

InChI

InChI=1S/C11H17BrN/c1-4-13(2,3)9-10-7-5-6-8-11(10)12/h5-8H,4,9H2,1-3H3/q+1

Molecular Formula

C11H17BrN+

HBD / HBA

- / -

Ikatan yang Dapat Dirotasi

3

Atom Berat

13

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Pertanyaan yang Sering Diajukan

An older antiarrhythmic medication that was used to treat life-threatening ventricular arrhythmias, including ventricular fibrillation, primarily in emergency settings. It works by blocking the release of norepinephrine from sympathetic nerve endings. It has largely been replaced by more effective and better-studied agents in advanced cardiac life support.

Yes, Bretylium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1199080. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 2431. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Struktur

Data Cepat

Rumus: C11H17BrN+

Tautan Eksternal

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Penyangkalan Medis

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.