Bromfenac Sodium

CHEMBL3181947 Phase 4 Disetujui Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
766.3 g/mol
LogP
Phase
4

The sodium salt of bromfenac, used as ophthalmic drops to manage ocular inflammation and pain after cataract surgery. Like the base compound, it inhibits prostaglandin synthesis in the eye to reduce post-surgical swelling and discomfort. It has a relatively long duration of action due to its ability to penetrate ocular tissues.

Berat Molekul

766,3000 g/mol

TPSA

169,00 Ų

Area Terapeutik

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Struktur 2D

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SMILES

Nc1c(CC(=O)[O-])cccc1C(=O)c1ccc(Br)cc1.Nc1c(CC(=O)[O-])cccc1C(=O)c1ccc(Br)cc1.O.O.O.[Na+].[Na+]

InChI

InChI=1S/2C15H12BrNO3.2Na.3H2O/c2*16-11-6-4-9(5-7-11)15(20)12-3-1-2-10(14(12)17)8-13(18)19;;;;;/h2*1-7H,8,17H2,(H,18,19);;;3*1H2/q;;2*+1;;;/p-2

Molecular Formula

C30H28Br2N2Na2O9

HBD / HBA

5 / 11

Ikatan yang Dapat Dirotasi

6

Atom Berat

45

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Pertanyaan yang Sering Diajukan

The sodium salt of bromfenac, used as ophthalmic drops to manage ocular inflammation and pain after cataract surgery. Like the base compound, it inhibits prostaglandin synthesis in the eye to reduce post-surgical swelling and discomfort. It has a relatively long duration of action due to its ability to penetrate ocular tissues.

Yes, Bromfenac Sodium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3181947. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 11954316. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

Penyangkalan Medis

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.