Buflomedil

CHEMBL188921 Phase 4 Disetujui Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

307.4 g/mol

LogP

2.3

Phase

4

A vasoactive drug used to treat peripheral arterial disease and symptoms of poor circulation, such as leg pain with walking. It works by relaxing blood vessel walls and reducing blood viscosity to improve tissue blood flow. It was withdrawn from several markets due to reports of serious cardiovascular and neurological adverse effects.

Berat Molekul

307,4000 g/mol

LogP

2,30

TPSA

48,00 Å²

Lipinski RO5

Lulus

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Struktur 2D

SVG PNG

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SMILES

COc1cc(OC)c(C(=O)CCCN2CCCC2)c(OC)c1

InChI

InChI=1S/C17H25NO4/c1-20-13-11-15(21-2)17(16(12-13)22-3)14(19)7-6-10-18-8-4-5-9-18/h11-12H,4-10H2,1-3H3

Molecular Formula

C17H25NO4

HBD / HBA

- / 5

Ikatan yang Dapat Dirotasi

8

Atom Berat

22

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Pertanyaan yang Sering Diajukan

A vasoactive drug used to treat peripheral arterial disease and symptoms of poor circulation, such as leg pain with walking. It works by relaxing blood vessel walls and reducing blood viscosity to improve tissue blood flow. It was withdrawn from several markets due to reports of serious cardiovascular and neurological adverse effects.

Yes, Buflomedil is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL188921. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 2467. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Struktur

Data Cepat

Rumus: C17H25NO4

Tautan Eksternal

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Penyangkalan Medis

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.