Butabarbital Sodium

CHEMBL1200982 Phase 4 Disetujui Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
234.2 g/mol
LogP
Phase
4

The sodium salt of butabarbital, a barbiturate sedative-hypnotic once used to treat insomnia and anxiety. Like other barbiturates, it has a significant risk of dependence, overdose, and drug interactions. It is rarely used today in the context of safer modern sleep aids.

Berat Molekul

234,2300 g/mol

TPSA

81,60 Ų

Mekanisme Kerja

Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mekanisme

Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.

Struktur 2D

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SMILES

CCC(C)C1(CC)C(=O)[N-]C(=O)NC1=O.[Na+]

InChI

InChI=1S/C10H16N2O3.Na/c1-4-6(3)10(5-2)7(13)11-9(15)12-8(10)14;/h6H,4-5H2,1-3H3,(H2,11,12,13,14,15);/q;+1/p-1

Molecular Formula

C10H15N2NaO3

HBD / HBA

1 / 3

Ikatan yang Dapat Dirotasi

3

Atom Berat

16

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Pertanyaan yang Sering Diajukan

The sodium salt of butabarbital, a barbiturate sedative-hypnotic once used to treat insomnia and anxiety. Like other barbiturates, it has a significant risk of dependence, overdose, and drug interactions. It is rarely used today in the context of safer modern sleep aids.

Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.

Yes, Butabarbital Sodium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200982. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 23690439. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

Penyangkalan Medis

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.