Calcifediol Anhydrous
The anhydrous form of calcifediol, the main circulating vitamin D metabolite used to treat vitamin D deficiency and related bone disorders, particularly in patients with chronic kidney disease. This form is used in specific extended-release formulations designed to raise vitamin D levels gradually. It bypasses the liver hydroxylation step needed to activate dietary vitamin D.
Berat Molekul
400,6000 g/mol
LogP
6,20
TPSA
40,50 Ų
Lipinski RO5
Lulus
Mekanisme Kerja
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.
Struktur 2D
Cite this structure
Embed this structure
SMILES
C=C1CC[C@H](O)C/C1=C/C=C1\CCC[C@]2(C)[C@@H]([C@H](C)CCCC(C)(C)O)CC[C@@H]12
InChI
InChI=1S/C27H44O2/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29/h11-12,20,23-25,28-29H,1,6-10,13-18H2,2-5H3/b21-11+,22-12-/t20-,23+,24-,25+,27-/m1/s1
Molecular Formula
C27H44O2
HBD / HBA
2 / 2
Ikatan yang Dapat Dirotasi
6
Atom Berat
29
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Pertanyaan yang Sering Diajukan
The anhydrous form of calcifediol, the main circulating vitamin D metabolite used to treat vitamin D deficiency and related bone disorders, particularly in patients with chronic kidney disease. This form is used in specific extended-release formulations designed to raise vitamin D levels gradually. It bypasses the liver hydroxylation step needed to activate dietary vitamin D.
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.
Yes, Calcifediol Anhydrous is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1040. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5283731. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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