Clomacran Phosphate
A phosphate salt form of clomacran that delivers the same antipsychotic effects as the parent compound. It is used to help control symptoms of psychosis and related mental health disorders.
Berat Molekul
398,8000 g/mol
TPSA
93,00 Ų
Mekanisme Kerja
Blocks dopamine D2 receptors in the mesolimbic pathway, reducing excessive dopaminergic neurotransmission associated with psychotic symptoms. Many also antagonize serotonin 5-HT2A receptors, which may improve negative symptoms and reduce extrapyramidal side effects.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Blocks dopamine D2 receptors in the mesolimbic pathway, reducing excessive dopaminergic neurotransmission associated with psychotic symptoms. Many also antagonize serotonin 5-HT2A receptors, which may improve negative symptoms and reduce extrapyramidal …
Struktur 2D
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SMILES
CN(C)CCCC1c2ccccc2Nc2ccc(Cl)cc21.O=P(O)(O)O
InChI
InChI=1S/C18H21ClN2.H3O4P/c1-21(2)11-5-7-14-15-6-3-4-8-17(15)20-18-10-9-13(19)12-16(14)18;1-5(2,3)4/h3-4,6,8-10,12,14,20H,5,7,11H2,1-2H3;(H3,1,2,3,4)
Molecular Formula
C18H24ClN2O4P
HBD / HBA
4 / 6
Ikatan yang Dapat Dirotasi
4
Atom Berat
26
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Pertanyaan yang Sering Diajukan
A phosphate salt form of clomacran that delivers the same antipsychotic effects as the parent compound. It is used to help control symptoms of psychosis and related mental health disorders.
Blocks dopamine D2 receptors in the mesolimbic pathway, reducing excessive dopaminergic neurotransmission associated with psychotic symptoms. Many also antagonize serotonin 5-HT2A receptors, which may improve negative symptoms and reduce extrapyramidal side effects.
Yes, Clomacran Phosphate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2104136. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 23724848. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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