Cortisone Acetate

CHEMBL1650 Phase 4 Disetujui Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

402.5 g/mol

LogP

2.1

Phase

4

The acetate ester of cortisone used as an oral or injectable corticosteroid for treating adrenal insufficiency and inflammatory conditions. As a prodrug, it is converted to active cortisol after administration.

Berat Molekul

402,5000 g/mol

LogP

2,10

TPSA

97,70 Å²

Lipinski RO5

Lulus

Area Terapeutik

Glaucoma Pain Management Rheumatoid Arthritis Asthma Chronic Obstructive Pulmonary Disease Generalized Anxiety Disorder Insomnia Melanoma Multiple Sclerosis Stroke Obesity Lymphoma Type 2 Diabetes Atopic Dermatitis Chronic Pain Prostate Cancer Leukemia

Mekanisme Kerja

Binds to intracellular glucocorticoid receptors, translocating to the nucleus to modulate gene transcription. This suppresses multiple inflammatory genes encoding cytokines, chemokines, and adhesion molecules while inducing anti-inflammatory proteins.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mekanisme

Binds to intracellular glucocorticoid receptors, translocating to the nucleus to modulate gene transcription. This suppresses multiple inflammatory genes encoding cytokines, chemokines, and adhesion molecules while inducing anti-inflammatory proteins.

Struktur 2D

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SMILES

CC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3C(=O)C[C@@]21C

InChI

InChI=1S/C23H30O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h10,16-17,20,28H,4-9,11-12H2,1-3H3/t16-,17-,20+,21-,22-,23-/m0/s1

Molecular Formula

C23H30O6

HBD / HBA

1 / 6

Ikatan yang Dapat Dirotasi

4

Atom Berat

29

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Pertanyaan yang Sering Diajukan

The acetate ester of cortisone used as an oral or injectable corticosteroid for treating adrenal insufficiency and inflammatory conditions. As a prodrug, it is converted to active cortisol after administration.

Binds to intracellular glucocorticoid receptors, translocating to the nucleus to modulate gene transcription. This suppresses multiple inflammatory genes encoding cytokines, chemokines, and adhesion molecules while inducing anti-inflammatory proteins.

Yes, Cortisone Acetate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1650. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5745. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Cortisone Acetate di PillFYI

Struktur

Data Cepat

Rumus: C23H30O6
Sinonim: 6

Tautan Eksternal

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Penyangkalan Medis

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.

Cortisone Acetate

Area Terapeutik

Mekanisme Kerja

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Struktur 2D

Cite this structure

Embed this structure

No targets recorded

No interactions recorded

No side effects recorded

Pertanyaan yang Sering Diajukan

References & Data Sources

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