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Dapsone

CHEMBL1043 Phase 4 Disetujui Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
248.3 g/mol
LogP
1.0
Phase
4

A sulfone antibiotic and anti-inflammatory agent originally developed for leprosy that also treats Pneumocystis pneumonia in immunocompromised patients and dermatitis herpetiformis. Topical dapsone gel is also approved for acne treatment.

Berat Molekul

248,3000 g/mol

LogP

1,00

TPSA

94,60 Ų

Lipinski RO5

Lulus

Area Terapeutik

Psoriasis Stroke Obesity Lymphoma Malaria Tuberculosis Colorectal Cancer Leukemia

Mekanisme Kerja

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mekanisme

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

Struktur 2D

SVG PNG

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SMILES

                    
Nc1ccc(S(=O)(=O)c2ccc(N)cc2)cc1

                

                

                
                

                    
InChI

                    
InChI=1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2

                

                

                

                    
                    

                        
Molecular Formula

                        
C12H12N2O2S

                    

                    
                    

                        
HBD / HBA

                        
2 / 4

                    

                    
                    

                        
Ikatan yang Dapat Dirotasi

                        
2

                    

                    
                    
                    

                        
Atom Berat

                        
17

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Pertanyaan yang Sering Diajukan

                

                    
                    

                        
                        

                            
A sulfone antibiotic and anti-inflammatory agent originally developed for leprosy that also treats Pneumocystis pneumonia in immunocompromised patients and dermatitis herpetiformis. Topical dapsone gel is also approved for acne treatment.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Dapsone is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1043.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 2955.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Penyangkalan Medis

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.