Delamanid

CHEMBL218650 Phase 4 Disetujui Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

534.5 g/mol

LogP

5.6

Phase

4

A nitro-dihydro-imidazooxazole antibiotic that inhibits mycobacterial cell wall synthesis by blocking the production of methoxy- and keto-mycolic acids, used for multidrug-resistant tuberculosis. It is reserved for TB cases where other options have been exhausted.

Berat Molekul

534,5000 g/mol

LogP

5,60

TPSA

104,00 Å²

Lipinski RO5

Gagal

Area Terapeutik

HIV/AIDS Tuberculosis

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Struktur 2D

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SMILES

C[C@]1(COc2ccc(N3CCC(Oc4ccc(OC(F)(F)F)cc4)CC3)cc2)Cn2cc([N+](=O)[O-])nc2O1

InChI

InChI=1S/C25H25F3N4O6/c1-24(15-31-14-22(32(33)34)29-23(31)38-24)16-35-18-4-2-17(3-5-18)30-12-10-20(11-13-30)36-19-6-8-21(9-7-19)37-25(26,27)28/h2-9,14,20H,10-13,15-16H2,1H3/t24-/m1/s1

Molecular Formula

C25H25F3N4O6

HBD / HBA

- / 11

Ikatan yang Dapat Dirotasi

7

Atom Berat

38

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Pertanyaan yang Sering Diajukan

A nitro-dihydro-imidazooxazole antibiotic that inhibits mycobacterial cell wall synthesis by blocking the production of methoxy- and keto-mycolic acids, used for multidrug-resistant tuberculosis. It is reserved for TB cases where other options have been exhausted.

Yes, Delamanid is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL218650. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 6480466. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Delamanid di PillFYI

Struktur

Data Cepat

Rumus: C25H25F3N4O6

Tautan Eksternal

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Penyangkalan Medis

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.