Diethylcarbamazine
An antiparasitic medication used to treat lymphatic filariasis (elephantiasis), loiasis, and tropical pulmonary eosinophilia caused by filarial worms. It works by killing the microfilariae stage of the parasites and immobilizing adult worms, making them susceptible to the immune system. Severe reactions can occur when large numbers of parasites are killed rapidly.
Berat Molekul
199,2900 g/mol
LogP
0,30
TPSA
26,80 Ų
Lipinski RO5
Lulus
Mekanisme Kerja
Disrupts essential metabolic pathways or structural components of parasitic organisms, leading to paralysis, starvation, or death of the parasite.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Disrupts essential metabolic pathways or structural components of parasitic organisms, leading to paralysis, starvation, or death of the parasite.
Struktur 2D
Cite this structure
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SMILES
CCN(CC)C(=O)N1CCN(C)CC1
InChI
InChI=1S/C10H21N3O/c1-4-12(5-2)10(14)13-8-6-11(3)7-9-13/h4-9H2,1-3H3
Molecular Formula
C10H21N3O
HBD / HBA
- / 2
Ikatan yang Dapat Dirotasi
2
Atom Berat
14
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Pertanyaan yang Sering Diajukan
An antiparasitic medication used to treat lymphatic filariasis (elephantiasis), loiasis, and tropical pulmonary eosinophilia caused by filarial worms. It works by killing the microfilariae stage of the parasites and immobilizing adult worms, making them susceptible to the immune system. Severe reactions can occur when large numbers of parasites are killed rapidly.
Disrupts essential metabolic pathways or structural components of parasitic organisms, leading to paralysis, starvation, or death of the parasite.
Yes, Diethylcarbamazine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL684. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 3052. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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