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Diltiazem Hydrochloride

CHEMBL1697 Phase 4 Disetujui Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
451.0 g/mol
LogP
—
Phase
4

The hydrochloride salt form of diltiazem, the standard pharmaceutical preparation used in oral and injectable formulations for hypertension, angina, and arrhythmias. It slows conduction through the AV node of the heart and dilates arteries. Available in immediate and extended-release formulations for different clinical needs.

Berat Molekul

451,0000 g/mol

TPSA

84,40 Ų

Area Terapeutik

Pain Management Gastroesophageal Reflux Disease Stroke Deep Vein Thrombosis / Pulmonary Embolism Obesity Type 2 Diabetes Hypertension Chronic Pain Hepatitis C Heart Failure Atrial Fibrillation Cardiovascular Disease Colorectal Cancer

Mekanisme Kerja

Benzothiazepine calcium channel blocker.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mekanisme

Benzothiazepine calcium channel blocker.

Struktur 2D

SVG PNG

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SMILES

                    
COc1ccc([C@@H]2Sc3ccccc3N(CCN(C)C)C(=O)[C@@H]2OC(C)=O)cc1.Cl

                

                

                
                

                    
InChI

                    
InChI=1S/C22H26N2O4S.ClH/c1-15(25)28-20-21(16-9-11-17(27-4)12-10-16)29-19-8-6-5-7-18(19)24(22(20)26)14-13-23(2)3;/h5-12,20-21H,13-14H2,1-4H3;1H/t20-,21+;/m1./s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C22H27ClN2O4S

                    

                    
                    

                        
HBD / HBA

                        
1 / 6

                    

                    
                    

                        
Ikatan yang Dapat Dirotasi

                        
7

                    

                    
                    
                    

                        
Atom Berat

                        
30

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Pertanyaan yang Sering Diajukan

                

                    
                    

                        
                        

                            
The hydrochloride salt form of diltiazem, the standard pharmaceutical preparation used in oral and injectable formulations for hypertension, angina, and arrhythmias. It slows conduction through the AV node of the heart and dilates arteries. Available in immediate and extended-release formulations for different clinical needs.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Benzothiazepine calcium channel blocker.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Diltiazem Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1697.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 62920.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Penyangkalan Medis

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.