Dimercaprol
A chelating agent, also known as BAL (British Anti-Lewisite), developed during World War II as an antidote to arsenic-containing chemical warfare agents. It is now used to treat poisoning with arsenic, mercury, and gold by binding to these metals and allowing their excretion. It must be given by painful intramuscular injection and itself carries significant toxicity.
Berat Molekul
124,2300 g/mol
LogP
0,20
TPSA
22,20 Ų
Lipinski RO5
Lulus
Area Terapeutik
Mekanisme Kerja
Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.
Struktur 2D
Cite this structure
Embed this structure
SMILES
OCC(S)CS
InChI
InChI=1S/C3H8OS2/c4-1-3(6)2-5/h3-6H,1-2H2
Molecular Formula
C3H8OS2
HBD / HBA
3 / 3
Ikatan yang Dapat Dirotasi
2
Atom Berat
6
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Pertanyaan yang Sering Diajukan
A chelating agent, also known as BAL (British Anti-Lewisite), developed during World War II as an antidote to arsenic-containing chemical warfare agents. It is now used to treat poisoning with arsenic, mercury, and gold by binding to these metals and allowing their excretion. It must be given by painful intramuscular injection and itself carries significant toxicity.
Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.
Yes, Dimercaprol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1597. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 3080. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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