Diosmin

CHEMBL231884 Phase 4 Disetujui Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
608.5 g/mol
LogP
-0.8
Phase
4

A flavonoid glycoside found naturally in certain plants, used to treat chronic venous insufficiency and hemorrhoids by strengthening and reducing the permeability of blood vessel walls and improving lymphatic drainage. It is often combined with hesperidin in standardized preparations. It is widely used in Europe for leg heaviness, swelling, and varicose veins.

Berat Molekul

608,5000 g/mol

LogP

-0,80

TPSA

234,00 Ų

Lipinski RO5

Gagal

Area Terapeutik

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Struktur 2D

SVG PNG

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SMILES

COc1ccc(-c2cc(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3o2)cc1O

InChI

InChI=1S/C28H32O15/c1-10-21(32)23(34)25(36)27(40-10)39-9-19-22(33)24(35)26(37)28(43-19)41-12-6-14(30)20-15(31)8-17(42-18(20)7-12)11-3-4-16(38-2)13(29)5-11/h3-8,10,19,21-30,32-37H,9H2,1-2H3/t10-,19+,21-,22+,23+,24-,25+,26+,27+,28+/m0/s1

Molecular Formula

C28H32O15

HBD / HBA

8 / 15

Ikatan yang Dapat Dirotasi

7

Atom Berat

43

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Pertanyaan yang Sering Diajukan

A flavonoid glycoside found naturally in certain plants, used to treat chronic venous insufficiency and hemorrhoids by strengthening and reducing the permeability of blood vessel walls and improving lymphatic drainage. It is often combined with hesperidin in standardized preparations. It is widely used in Europe for leg heaviness, swelling, and varicose veins.

Yes, Diosmin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL231884. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 5281613. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

Penyangkalan Medis

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.