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Duloxetine Hydrochloride

CHEMBL1200328 Phase 4 Disetujui Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
333.9 g/mol
LogP
—
Phase
4

A hydrochloride salt form of duloxetine used to treat major depressive disorder, generalized anxiety disorder, and chronic pain conditions. Like the base form, it boosts serotonin and norepinephrine levels in the brain.

Berat Molekul

333,9000 g/mol

TPSA

49,50 Ų

Area Terapeutik

Infectious Disease Respiratory Disease Pain Management Ophthalmology Chronic Obstructive Pulmonary Disease Alzheimer's Disease Parkinson's Disease Epilepsy Migraine Schizophrenia Bipolar Disorder Generalized Anxiety Disorder Insomnia Gastroesophageal Reflux Disease Inflammatory Bowel Disease Systemic Lupus Erythematosus Multiple Sclerosis Chronic Kidney Disease Non-Alcoholic Fatty Liver Disease Oncology Stroke Type 2 Diabetes Major Depressive Disorder Breast Cancer Chronic Pain Cardiovascular Disease Prostate Cancer Colorectal Cancer

Mekanisme Kerja

Serotonin-norepinephrine reuptake inhibitor (SNRI).

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mekanisme

Serotonin-norepinephrine reuptake inhibitor (SNRI).

Struktur 2D

SVG PNG

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SMILES

                    
CNCC[C@H](Oc1cccc2ccccc12)c1cccs1.Cl

                

                

                
                

                    
InChI

                    
InChI=1S/C18H19NOS.ClH/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16;/h2-10,13,17,19H,11-12H2,1H3;1H/t17-;/m0./s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C18H20ClNOS

                    

                    
                    

                        
HBD / HBA

                        
2 / 3

                    

                    
                    

                        
Ikatan yang Dapat Dirotasi

                        
6

                    

                    
                    
                    

                        
Atom Berat

                        
22

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Pertanyaan yang Sering Diajukan

                

                    
                    

                        
                        

                            
A hydrochloride salt form of duloxetine used to treat major depressive disorder, generalized anxiety disorder, and chronic pain conditions. Like the base form, it boosts serotonin and norepinephrine levels in the brain.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Serotonin-norepinephrine reuptake inhibitor (SNRI).

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Duloxetine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1200328.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 60834.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Penyangkalan Medis

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.