Edrophonium
A short-acting cholinesterase inhibitor used to diagnose myasthenia gravis and to reverse neuromuscular blockade after surgery. It temporarily increases the availability of acetylcholine at nerve-muscle junctions.
Berat Molekul
166,2400 g/mol
LogP
1,80
TPSA
20,20 Ų
Lipinski RO5
Lulus
Mekanisme Kerja
Blocks neuromuscular transmission at the motor end plate by competing with acetylcholine for nicotinic receptor binding sites, producing skeletal muscle relaxation and paralysis.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Blocks neuromuscular transmission at the motor end plate by competing with acetylcholine for nicotinic receptor binding sites, producing skeletal muscle relaxation and paralysis.
Struktur 2D
Cite this structure
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SMILES
CC[N+](C)(C)c1cccc(O)c1
InChI
InChI=1S/C10H15NO/c1-4-11(2,3)9-6-5-7-10(12)8-9/h5-8H,4H2,1-3H3/p+1
Molecular Formula
C10H16NO+
HBD / HBA
1 / 1
Ikatan yang Dapat Dirotasi
2
Atom Berat
12
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Pertanyaan yang Sering Diajukan
A short-acting cholinesterase inhibitor used to diagnose myasthenia gravis and to reverse neuromuscular blockade after surgery. It temporarily increases the availability of acetylcholine at nerve-muscle junctions.
Blocks neuromuscular transmission at the motor end plate by competing with acetylcholine for nicotinic receptor binding sites, producing skeletal muscle relaxation and paralysis.
Yes, Edrophonium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1104. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 3202. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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