Elapegademase
This enzyme replacement therapy provides a working version of adenosine deaminase, an enzyme missing in a rare form of severe combined immunodeficiency. Regular injections help restore immune system function in affected patients.
Berat Molekul
248,2800 g/mol
LogP
-2,70
TPSA
111,00 Ų
Lipinski RO5
Lulus
Mekanisme Kerja
Provides exogenous replacement of the deficient or absent enzyme, enabling the metabolic processing of accumulated substrates and restoring normal metabolic function.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Provides exogenous replacement of the deficient or absent enzyme, enabling the metabolic processing of accumulated substrates and restoring normal metabolic function.
Struktur 2D
Cite this structure
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SMILES
COCCOC(=O)NCCCC[C@@H](C(=O)O)N
InChI
InChI=1S/C10H20N2O5/c1-16-6-7-17-10(15)12-5-3-2-4-8(11)9(13)14/h8H,2-7,11H2,1H3,(H,12,15)(H,13,14)/t8-/m0/s1
Molecular Formula
C10H20N2O5
HBD / HBA
3 / 6
Ikatan yang Dapat Dirotasi
10
Atom Berat
17
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Pertanyaan yang Sering Diajukan
This enzyme replacement therapy provides a working version of adenosine deaminase, an enzyme missing in a rare form of severe combined immunodeficiency. Regular injections help restore immune system function in affected patients.
Provides exogenous replacement of the deficient or absent enzyme, enabling the metabolic processing of accumulated substrates and restoring normal metabolic function.
Yes, Elapegademase is an approved drug. It has reached clinical phase 4. It is classified as a Enzyme.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3990026. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 121488177. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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