Estramustine Phosphate

CHEMBL1756 Phase 4 Disetujui Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

520.4 g/mol

LogP

2.9

Phase

4

This medication combines estrogen and a nitrogen mustard chemotherapy agent to target and kill prostate cancer cells. It works both hormonally and by disrupting cancer cell division.

Berat Molekul

520,4000 g/mol

LogP

2,90

TPSA

96,30 Å²

Lipinski RO5

Lulus

Area Terapeutik

Bladder Cancer Lymphoma Breast Cancer Prostate Cancer Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Struktur 2D

SVG PNG

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SMILES

C[C@]12CC[C@@H]3c4ccc(OC(=O)N(CCCl)CCCl)cc4CC[C@H]3[C@@H]1CC[C@@H]2OP(=O)(O)O

InChI

InChI=1S/C23H32Cl2NO6P/c1-23-9-8-18-17-5-3-16(31-22(27)26(12-10-24)13-11-25)14-15(17)2-4-19(18)20(23)6-7-21(23)32-33(28,29)30/h3,5,14,18-21H,2,4,6-13H2,1H3,(H2,28,29,30)/t18-,19-,20+,21+,23+/m1/s1

Molecular Formula

C23H32Cl2NO6P

HBD / HBA

2 / 6

Ikatan yang Dapat Dirotasi

8

Atom Berat

33

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Pertanyaan yang Sering Diajukan

This medication combines estrogen and a nitrogen mustard chemotherapy agent to target and kill prostate cancer cells. It works both hormonally and by disrupting cancer cell division.

Yes, Estramustine Phosphate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1756. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 259329. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Struktur

Data Cepat

Rumus: C23H32Cl2NO6P

Tautan Eksternal

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Penyangkalan Medis

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.