Fluoroestradiol F-18
This fluorine-18 labeled estradiol analog is used as a PET radiotracer to image estrogen receptor expression in breast cancer lesions.
Berat Molekul
289,4000 g/mol
LogP
3,50
TPSA
40,50 Ų
Lipinski RO5
Lulus
Area Terapeutik
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Struktur 2D
Cite this structure
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SMILES
C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1C[C@@H]([18F])[C@@H]2O
InChI
InChI=1S/C18H23FO2/c1-18-7-6-13-12-5-3-11(20)8-10(12)2-4-14(13)15(18)9-16(19)17(18)21/h3,5,8,13-17,20-21H,2,4,6-7,9H2,1H3/t13-,14-,15+,16-,17+,18+/m1/s1/i19-1
Molecular Formula
C18H23FO2
HBD / HBA
2 / 3
Ikatan yang Dapat Dirotasi
0
Atom Berat
21
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Pertanyaan yang Sering Diajukan
This fluorine-18 labeled estradiol analog is used as a PET radiotracer to image estrogen receptor expression in breast cancer lesions.
Yes, Fluoroestradiol F-18 is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL4594261. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 10869981. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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