Flupirtine

CHEMBL255044 Phase 4 Disetujui Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

304.3 g/mol

LogP

2.4

Phase

4

This non-opioid analgesic works by activating potassium channels and modulating NMDA receptors to relieve chronic musculoskeletal pain.

Berat Molekul

304,3200 g/mol

LogP

2,40

TPSA

89,30 Å²

Lipinski RO5

Lulus

Area Terapeutik

Pain Management Multiple Sclerosis Chronic Pain

Mekanisme Kerja

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission and modulates the emotional response to pain.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mekanisme

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission …

Struktur 2D

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SMILES

CCOC(=O)Nc1ccc(NCc2ccc(F)cc2)nc1N

InChI

InChI=1S/C15H17FN4O2/c1-2-22-15(21)19-12-7-8-13(20-14(12)17)18-9-10-3-5-11(16)6-4-10/h3-8H,2,9H2,1H3,(H,19,21)(H3,17,18,20)

Molecular Formula

C15H17FN4O2

HBD / HBA

3 / 6

Ikatan yang Dapat Dirotasi

6

Atom Berat

22

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Pertanyaan yang Sering Diajukan

This non-opioid analgesic works by activating potassium channels and modulating NMDA receptors to relieve chronic musculoskeletal pain.

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission and modulates the emotional response to pain.

Yes, Flupirtine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL255044. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 53276. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Struktur

Data Cepat

Rumus: C15H17FN4O2

Tautan Eksternal

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Penyangkalan Medis

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.